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Cetirizine Dihydrochloride  
Chemical Name [2-{4-(4-Chlorophenyl)phenylemethyl)-1-Piperazynyl} Ethoxy] Acetic acid Dihydrochloride
CAS No. 83881-52-1
Molecular Formula C21 H27 CI3N2O3
 
Molecular Weight 461.89
Description White to off  white crystalline powder.
Solubility  A Clear solution in water,soluble Methanol
Identification (a) Light absorption at 231 nm shows maxima
      Specific absorbence at maximum 359-381.
(b) By I.R
(c) By T.L.C
Melting Range 218 0 C to 220 0 C
Appearance of solution A 5% w/v solution(solution S)in water is not more intensely
coloured than ref. By. 7.
ph of solution The pH of solution S is 1.2 - 1.8.
Related substances By HPLC
Heavy Metals NMT 10 ppm.
Moisture Content NMT 0.5 % w/w
Loss on Drying NMT 0.5 % w/w.
Sulphated Ash NMT 0.2 % w/w.
Assay NLT 99 % w/w
End Use
Antihistamine.
Packaging and Labelling
The substance is packed in Fibre Drums. 25 Kg./50 Kg.
Each packaging is identified with a label including the substance name, net mass, manufacturer name and lot number.
Storage
Store in a dry place at temperature below 25°C and protect from light.